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Energy Coupling and Phosphorylation

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State

Energy coupling pairs ATP hydrolysis with an endergonic reaction, often by phosphorylation — transferring ATP's terminal phosphate onto another molecule.

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The sodium-potassium pump from Bio 0362 is phosphorylated by ATP, and that transfer drives the conformational change moving sodium and potassium.

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The energy does not leap to the second reaction — phosphorylation physically links the two.