Biology / Unit 3 Bio 0522 short lesson, about 20 seconds
Enzyme Denaturation
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The idea
Denaturation is a change to an enzyme's natural shape, usually from extreme heat or pH, that disrupts its active site and destroys its function.
In practice
An enzyme exposed to boiling temperatures loses its functional shape and cannot bind its substrate again, even after cooling.
Where people slip
Denaturation changes an enzyme's structure, not its amino acid sequence — the underlying protein chain is not broken apart.
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