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Biology / Unit 3   Bio 0530 short lesson, about 20 seconds

Enzyme Compartmentalization

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The idea

Compartmentalizing enzymes inside specific organelles restricts where and when they act on their substrates, adding control beyond the enzyme's own binding.

In practice

The citric acid cycle's later enzymes work only inside the mitochondrion, kept apart from the rest of the cytoplasm.

Where people slip

Compartmentalization controls substrate access, not intrinsic activity — the same enzyme could still function if relocated.

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