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Biology / Unit 3   Bio 0544 short lesson, about 20 seconds

Pyruvate Oxidation to Acetyl CoA

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The idea

Pyruvate entering the mitochondrion loses a carbon as carbon dioxide, transfers electrons to NAD+, and joins coenzyme A to form acetyl CoA.

In practice

This three-step conversion happens twice per original glucose molecule, once for each pyruvate glycolysis produced.

Where people slip

This step, not glycolysis itself, is where the first carbon from glucose leaves the cell as carbon dioxide.

Your place on the trail

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