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Biology / Unit 4   Bio 0859 short lesson, about 20 seconds

Prometaphase and the Kinetochore

Captions available

The idea

Prometaphase is the stage where the nuclear envelope finishes fragmenting and each sister chromatid grows a kinetochore, a protein structure at the centromere that binds spindle microtubules.

In practice

Spindle microtubules extending from opposite poles attach to a chromosome's two kinetochores, one set from each pole.

Where people slip

A chromosome is not secured until both sister chromatids' kinetochores attach to microtubules from opposite poles.

Your place on the trail

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