Biology / Unit 4 Bio 0809 short lesson, about 20 seconds
Signal Transduction Can Regulate Gene Expression
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The idea
A signaling pathway can regulate gene expression when its final activated protein enters the nucleus and controls transcription or translation there.
In practice
A phosphorylated inhibitor protein can release a bound transcription factor, letting that factor enter the nucleus and switch on RNA transcription.
Where people slip
Only the pathway's final, nucleus-bound step directly changes gene expression — the earlier cascade steps only relay the signal there.
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