Adrenal Cortex versus Adrenal Medulla
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The adrenal cortex, an outer layer, produces steroid hormones including cortisol and aldosterone; the adrenal medulla, an inner region of neural origin, produces epinephrine and norepinephrine.
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The adrenal medulla is innervated by sympathetic fibers, releasing hormones on rapid neural command rather than slow signaling.
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The two adrenal regions differ in embryonic origin and hormone type — not two layers of one tissue.