Biology / Unit 12 Bio 2925 short lesson, about 20 seconds
Plasma Membrane Receptors and cAMP Second Messenger
Captions available
The idea
A water-soluble hormone binds a surface receptor, activating a G-protein that triggers adenylyl cyclase to convert ATP into cyclic AMP, per Bio 0805, amplifying the signal inside the cell.
In practice
A sprinter's epinephrine surge triggers G-protein cascades producing many cAMP molecules per receptor, amplifying the signal body-wide.
Where people slip
Phosphodiesterase continuously breaks down cAMP, so the signal terminates once hormone binding stops.
Your place on the trail
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