One Molecule Can Signal as Both Hormone and Neurotransmitter
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What distinguishes a hormone from a neurotransmitter is release site and distance, not identity — a neurotransmitter acts locally at a synapse, a hormone travels through blood to targets.
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Norepinephrine released at a synapse acts within microns; released into blood, the same molecule reaches organs body-wide.
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"Hormones and neurotransmitters are entirely different," per Bio 2927, mistakes a role split for chemical split.