Lysosomes
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A lysosome is an animal-cell organelle that digests proteins, polysaccharides, lipids, nucleic acids, and worn-out organelles using enzymes active at low pH.
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A macrophage engulfs a bacterium into a vesicle, which then fuses with a lysosome so the enzymes inside can destroy the pathogen.
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Most plant cells lack lysosomes and carry out equivalent digestion inside the vacuole instead.