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Post-Transcriptional Regulation: Alternative Splicing

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Alternative splicing joins a pre-mRNA's exons in more than one combination, letting a single gene produce more than one protein.

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A pre-mRNA with four exons can be spliced to include all four, or skip one, producing two mRNAs from the same gene.

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Alternative splicing changes which exons are included, not the sequence within any exon — it recombines exons, not new coding.