Skip to main content

"The Genome Fully Predicts the Proteome"

This video presents the same text shown beside it, spoken and on screen. It adds nothing the text does not say.

State

A genome does not fully predict its proteome, because alternative splicing and post-translational modification add diversity the DNA sequence alone does not fix.

Show

Alternative splicing of one gene's pre-mRNA, per Bio 1331, produces more than one protein from a single sequence.

Watch for

A genome sets which proteins are possible; splicing and modification, not the genome alone, determine which proteins a cell actually makes.