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Biology / Unit 6   Bio 1279 short lesson, about 20 seconds

The 5' and 3' Untranslated Regions

Captions available

The idea

A mature mRNA's untranslated regions flank the coding sequence, upstream of the start codon and downstream of the stop codon.

In practice

The 5' region sits between cap and start codon; the 3' region sits between stop codon and poly-A tail.

Where people slip

An untranslated region is still transcribed and spliced with the mRNA — only its translation into protein is what it lacks.

Your place on the trail

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