The Reading Frame
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The reading frame is the specific grouping of an mRNA sequence into consecutive, non-overlapping codons, fixed by where translation begins.
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The sequence AUGGGCUAA reads as AUG-GGC-UAA in its correct frame, but as a different, meaningless set of codons if shifted by one base.
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An mRNA has three possible reading frames, but the start codon fixes which one is actually translated.