Biology / Unit 6 Bio 1253 short lesson, about 20 seconds
The Wobble Hypothesis
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The idea
The wobble hypothesis holds that a tRNA's third anticodon position can pair loosely with more than one codon base, letting fewer tRNAs read a degenerate code.
In practice
One tRNA's wobble position can pair with either of two codons that differ only in their third base.
Where people slip
Wobble pairing is restricted to a codon's third position — the first two positions must still pair exactly.
Your place on the trail
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Builds on
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