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Biology / Unit 9   Bio 1913 short lesson, about 20 seconds

Baltimore Groups IV–VII and Retroviruses

Captions available

The idea

Groups IV and V carry single-stranded RNA read or copied into mRNA; Groups VI and VII use reverse transcriptase to make DNA from RNA.

In practice

HIV, a Group VI retrovirus, reverse-transcribes its RNA genome into DNA before inserting it into the host cell's genome.

Where people slip

Reverse transcription runs counter to a cell's usual DNA-to-RNA direction— retroviruses are the named exception, not the rule.

Your place on the trail

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