DNA Methylation
This video presents the same text shown beside it, spoken and on screen. It adds nothing the text does not say.
State
DNA methylation adds a methyl group directly to certain DNA bases, typically silencing the gene's transcription without changing its sequence.
Show
Heavily methylated DNA near a gene's promoter is generally associated with that gene being transcribed less or not at all.
Watch for
Methylation, like histone modification, is an epigenetic change — it alters gene expression without altering the DNA sequence a mutation would change.