Biology / Unit 6 Bio 1301 short lesson, about 20 seconds
Point Mutations: Nonsense
Captions available
The idea
A nonsense mutation changes a codon into a premature stop codon, ending translation early and producing a shortened, usually nonfunctional protein.
In practice
A single base change converting a tyrosine codon into a stop codon halts the ribosome partway through the intended protein.
Where people slip
A nonsense mutation is a single base change like missense, but its effect on the protein is far more disruptive.
Your place on the trail
Every lesson rests on earlier ones and opens later ones. Tap any to jump.
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