Point Mutations: Nonsense
This video presents the same text shown beside it, spoken and on screen. It adds nothing the text does not say.
State
A nonsense mutation changes a codon into a premature stop codon, ending translation early and producing a shortened, usually nonfunctional protein.
Show
A single base change converting a tyrosine codon into a stop codon halts the ribosome partway through the intended protein.
Watch for
A nonsense mutation is a single base change like missense, but its effect on the protein is far more disruptive.