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Levels of Gene-Expression Regulation, Overview

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Gene expression is regulated at several levels, including epigenetic, transcriptional, post-transcriptional, translational, and post-translational control.

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A cell can silence a gene by packaging its DNA tightly, blocking transcription, degrading its mRNA, blocking translation, or degrading the finished protein.

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These levels act at different stages along the central dogma — a change at one level need not imply a matching change at another.