Biology / Unit 6 Bio 1299 short lesson, about 20 seconds
Point Mutations: Missense
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The idea
A missense mutation changes a single DNA nucleotide so that the resulting codon specifies a different amino acid than the original sequence.
In practice
Sickle-cell disease arises from a single missense mutation swapping one amino acid for another in the beta-globin protein.
Where people slip
This entry names sickle-cell disease strictly as an example of how one base change alters one amino acid, not as health guidance.
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