Biology / Unit 6 Bio 1269 short lesson, about 20 seconds
Eukaryotic Transcription Factors Assembling the Initiation Complex
Captions available
The idea
Eukaryotic transcription factors bind a gene's promoter and assemble a complex that recruits RNA polymerase II, which cannot bind the promoter unassisted.
In practice
Several basal transcription factors bind the TATA box in sequence, each stabilizing the complex before RNA polymerase II joins.
Where people slip
Prokaryotic RNA polymerase needs only sigma factor to find a promoter — eukaryotic RNA polymerase II needs a whole assembled complex.
Your place on the trail
Every lesson rests on earlier ones and opens later ones. Tap any to jump.
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