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Biology / Unit 6   Bio 1243 short lesson, about 20 seconds

Nucleotide Excision Repair

Captions available

The idea

Nucleotide excision repair removes a damaged DNA stretch, such as one from ultraviolet light, and resynthesizes it from the intact complementary strand.

In practice

UV damage that distorts the helix is cut out on both sides, and DNA polymerase and ligase fill and seal the gap.

Where people slip

This pathway repairs damage from an external source such as UV — mismatch repair already handles replication errors.

Your place on the trail

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