Biology / Unit 6 Bio 1241 short lesson, about 20 seconds
Mismatch Repair
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The idea
Mismatch repair scans newly replicated DNA for base pairs proofreading missed, then removes and correctly resynthesizes the surrounding stretch of the new strand.
In practice
A mismatch-repair complex detects a mispaired base, distinguishes the newer strand from the template, and replaces the incorrect section.
Where people slip
Mismatch repair targets errors from replication itself — nucleotide excision repair, covered next, targets damage from outside sources instead.
Your place on the trail
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