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Biology / Unit 5   Bio 1045 short lesson, about 20 seconds

Lethal Alleles

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The idea

A lethal allele causes death, often in the homozygous state, before or shortly after birth, skewing an observed offspring ratio from its expected value.

In practice

A cross expected to produce a 1:2:1 genotype ratio can appear as 2:1 if the homozygous class dies before birth uncounted.

Where people slip

A skewed ratio is evidence to investigate, not evidence Mendelian inheritance failed — segregation still holds.

Your place on the trail

Every lesson rests on earlier ones and opens later ones. Tap any to jump.

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