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The Physical Basis of Segregation in Meiosis I

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The law of segregation's physical basis is anaphase I, where homologous chromosomes carrying an organism's two alleles separate to opposite poles.

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A heterozygous cell's Y-bearing and y-bearing homologs separate at anaphase I — described only decades after Mendel's work.

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Mendel deduced segregation from breeding ratios alone — the meiotic mechanism behind it was discovered after his death.

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