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Human Growth and Development / Unit 2   HGD 0163 short lesson, about 20 seconds

Pleiotropy and PKU

Captions available

The idea

Pleiotropy is one gene influencing several traits, as in phenylketonuria, or PKU, where the body cannot metabolise the amino acid phenylalanine.

In practice

Untreated PKU bringing cognitive disability, eczema and delayed growth from a single recessive gene.

Where people slip

PKU is treated by limiting phenylalanine in the diet; it affects about one in ten thousand to fifteen thousand births.

Your place on the trail

Every lesson rests on earlier ones and opens later ones. Tap any to jump.

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