Biology / Unit 4 Bio 0887 worked example, 60 to 90 seconds
The Cyclin-Cdk Activation Cycle
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The idea
A cyclin-dependent kinase becomes fully active only after binding a cyclin and then being phosphorylated at a specific site, and that active complex is dismantled again once the cyclin it depends on is degraded.
Where people slip
Cdk activity depends on two separate conditions holding at once, cyclin binding and site-specific phosphorylation — satisfying only one leaves the complex inactive.
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