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Biology / Unit 4   Bio 0881 short lesson, about 20 seconds

The G2 Checkpoint

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The idea

The G2 checkpoint bars entry into the mitotic phase unless chromosome replication is complete and the DNA is undamaged.

In practice

A cell whose G2 checkpoint detects incomplete replication halts there and attempts to finish or repair the damage.

Where people slip

The G2 checkpoint's central concern is DNA integrity — size and reserves are checked too, but damage detection mainly gates this.

Your place on the trail

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