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Platelets and the Clotting Cascade

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State

Platelets, cell fragments rather than whole cells, trigger a clotting cascade that amplifies through positive feedback, per Bio 2751, until a fibrin clot seals a vessel injury.

Show

Platelets aggregating at a cut activate more clotting factors until the fibrin mesh halts blood loss.

Watch for

The clotting cascade is a healthy example of positive feedback, per Bio 2751, not evidence of malfunction.