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Protein Digestion

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Protein digestion begins with pepsin in the stomach cleaving proteins into peptides, continues with pancreatic trypsin, chymotrypsin, and elastase, and finishes with peptidases yielding free amino acids.

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Carboxypeptidase and aminopeptidase trim peptides down to single amino acids at the intestinal lining.

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Pepsin also activates more of its own precursor, a small positive feedback loop within an otherwise negative-feedback system.