Vesicles and Vacuoles
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Vesicles and vacuoles are membrane-bound sacs for storage and transport, differing mainly in that a vacuole is larger and does not fuse with other membranes.
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A transport vesicle can bud from one organelle's membrane and fuse with another's, carrying its cargo between them.
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A vesicle's membrane fuses readily with others; a vacuole's membrane does not.