Hypersensitivity and Allergy Mechanism
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An allergic reaction is a hypersensitivity response in which the allergy-linked antibody class, per Bio 3285, reacts strongly to a normally harmless antigen.
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Mast cells coated with this antibody release histamine on re-exposure, producing allergic symptoms.
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The damage comes from the immune response itself, not from the allergen, which is harmless to almost everyone else.