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Biology / Unit 2   Bio 0330 short lesson, about 20 seconds

Cholesterol's Role in the Membrane

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The idea

Cholesterol sits alongside membrane phospholipids and buffers the effect of temperature, keeping the membrane fluid at low temperatures and less fluid at high ones.

In practice

Animal cell membranes hold cholesterol between phospholipid tails, widening the temperature range across which the membrane still functions.

Where people slip

Cholesterol moderates fluidity in both directions at once — a buffer, not a fluidizer or stiffener alone.

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