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The Bohr Effect

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The Bohr effect describes how rising carbon dioxide and falling pH at active tissue shift hemoglobin's dissociation curve rightward, per Bio 3163, releasing oxygen more readily where needed.

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Exercising muscle's acidic, CO2-rich environment triggers greater oxygen release than resting tissue does.

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The Bohr effect adjusts local oxygen release — it does not change uptake at the lungs.