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Biology / Unit 7   Bio 1581 short lesson, about 20 seconds

Sequence Alignment and BLAST

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The idea

Sequence alignment arranges DNA, RNA, or protein sequences to identify shared regions; BLAST is software that searches a database for sequences matching a query.

In practice

Entering one short DNA sequence into BLAST returns every location in a chosen genome with a closely matching sequence.

Where people slip

A BLAST match shows sequence similarity at the searched region — it does not establish identical function.

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