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Biology / Unit 6   Bio 1219 short lesson, about 20 seconds

Primase and the RNA Primer

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The idea

Primase synthesizes a short RNA primer complementary to the DNA template, giving DNA polymerase the starting point it needs.

In practice

A primer roughly five to ten nucleotides long is laid down before DNA polymerase adds a single DNA nucleotide.

Where people slip

DNA polymerase cannot start a strand from nothing — every new DNA strand begins from an RNA primer, later removed and replaced.

Your place on the trail

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