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Biology / Unit 6   Bio 1213 short lesson, about 20 seconds

"DNA Replication Keeps One Whole Original Helix Intact"

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The idea

The conservative-replication model, ruled out by Meselson and Stahl, wrongly predicted one original helix stays intact while an entirely new copy forms.

In practice

Conservative replication would have produced two separate density bands after one replication round; Meselson and Stahl found one intermediate band instead.

Where people slip

An intermediate-density band is direct evidence against this model — it is exactly what semiconservative replication predicts.

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