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Amphoterism at the Metal-Nonmetal Boundary

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Per Chem 1809's amphoteric definition, elements and compounds near the metal-nonmetal boundary of the periodic table characteristically react with both acids and bases.

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Aluminum hydroxide dissolves in strong acid and in strong base alike, but not in water alone.

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Amphoteric is not the same as neutral — an amphoteric substance reacts readily with either type of reagent rather than with neither.

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