Antifungal Treatment Difficulty
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Fungi are eukaryotic, like their animal hosts, so a compound that disrupts fungal cell processes often disrupts the host's cells as well.
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Standard antibiotics target only prokaryotic-specific structures and have no effect on a eukaryotic fungal pathogen at all.
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This eukaryote-on-eukaryote similarity, not any lack of research effort, is the core reason antifungal drugs carry more side effects than typical antibiotics.